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health1d ago
Scientists Can Finally Explain Rare Blood Clots Linked to COVID Vaccines
- An international study of 100 VITT patients shows antibodies that bind platelet factor 4 very tightly after a specific antibody change.
- The antibodies likely originate from memory of prior adenovirus infections, linking to an adenoviral protein called protein VII.
- A second rare event is needed: inheriting a particular immune gene variant that shapes antibody structure.
- Researchers say VITT is rare because both the genetic variant and the mutation must occur together.
- Adenovirus-based vaccines remain important tools; understanding VITT could guide safer future vaccines.
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