8legs: University of new mexico

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#1 out of 310.1K est. views

Researchers identify OTULIN as a possible master regulator of genes linked to brain aging and neurodegeneration.
Blocking OTULIN activity reduced the Alzheimer’s-related protein tau in human neuron cultures.
Complete removal of the OTULIN gene halted tau production in neurons studied.
OTULIN also influences RNA metabolism and gene expression beyond tau.
Researchers caution OTULIN targeting is not yet feasible for therapy due to broad bodily roles.
Findings point to OTULIN as a potential new target for anti-aging and neurodegeneration research.
RNA sequencing revealed OTULIN removal affects inflammation-related gene activity in neurons.
The study appeared in Genomic Psychiatry and used human tissue cultures and stem-cell–derived neurons.
Scientists emphasize OTULIN’s role in clearing cellular waste including tau tangles.

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#2 out of 3

sports23h ago

New Mexico rolled to an 89-61 victory over UNLV in Las Vegas, with Buljan pouring in 18 points.
Buljan also grabbed 11 rebounds to post a double-double for the Lobos.
Jake Hall added 16 points on 7-of-11 shooting to support the offense.
Uriah Tenette finished with 15 points, efficient from the line.
UNLV’s Isaac Williamson led the Rebels with nine points in the loss.
The Lobos built a 41-22 halftime lead and never looked back.
New Mexico improved to 17-4 overall and 8-2 in Mountain West play.
The AP cited data from Sportradar and technology from Data Skrive in covering the game.
The Rebels fall to 10-10 overall, 5-4 in conference play after the defeat.
The game continued a strong season for New Mexico, keeping them near the top of the Mountain West.

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#3 out of 3

sports17h ago

Pastner acknowledged a tough loss as UNLV fell 89-61 to New Mexico, impacting their conference outlook.
The Rebels extended the nation’s longest streak of making at least one three-pointer, a record dating back 39 years.
Pastner emphasized urgency after the loss, noting the upcoming road game against Nevada in 72 hours.
Freshman Issac Williamson contributed minutes and commented on the team’s effort despite the defeat.
Pastner gave credit to New Mexico and admitted the team must be better after the setback.
The Lobos controlled the game, building a sizable lead and hurting UNLV on both ends.
UNLV’s season trajectory faced renewed scrutiny following the lopsided defeat.
Pastner’s remarks referenced the need for toughness ahead of the Nevada game.
The game highlighted the Rebels’ struggle to sustain offensive momentum.
The report notes NAAS Cunningham contributed meaningful minutes as part of the team’s effort.

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