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The London couple at the heart of 'first-of-its-kind' Alzheimer's treatment
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The London couple at the heart of 'first-of-its-kind' Alzheimer's treatment

  • London couple participate in a pioneering Alzheimer’s trial at UCLH led by Professor Catherine Mummery.
  • Penny Horton was diagnosed with early-onset Alzheimer’s after extensive tests and evaluations.
  • Researchers report no adverse side effects and early signals of improvement in the trial.
  • The trial focuses on ImmunoBrain’s antibody therapy aiming to modulate the immune system in Alzheimer's.
  • Denis Horton emphasizes patience as they adapt to changes in Penny’s memory and daily life.
  • The study underscores the need for volunteers to drive progress in Alzheimer’s research.
  • Penny and Denis were married for 45 years and met in Grimsby before moving to London.
  • The research is described as an early-stage investigation with promising early signals.
  • The trial’s leadership aims to slow disease progression by addressing brain inflammation.
  • The Horton family remains active in theatre-going and walking, illustrating the human impact of the condition.
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