#1
#1 out of 216.3K est. views
health1d ago
Scientists Identify an Epigenetic Switch That Can Slow Production of Fat Cells
- Researchers show an epigenetic switch can slow fat cell production by altering the Hippo-YAP/TAZ pathway in mice.
- Blocking PPARγ’s fat‑cell instructions kept cells in a less specialized state and reduced adipocyte formation in mouse models.
- When Hippo pathway brakes were released in mice, YAP and TAZ became hyperactive and fat cells regressed toward precursor-like states.
- The study suggests epigenetic regulation plays a key role in adipocyte identity and could inform metabolic disease therapies.
- The work was published in Science Advances, signaling a foundation for future personalized approaches to metabolic diseases.
Vote 0
