8legs: Plos biology

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#1 out of 256.2K est. views92.59%

4h ago

New space study shows phages and bacteria evolve differently in microgravity on the ISS.
Researchers infected E. coli with T7 phage aboard the ISS and compared results with Earth.
Space mutations boosted phage infectivity and altered bacterial defenses.
Mutations in the T7 protein may underlie increased infection in microgravity.
Space-driven bacterial mutations could enhance survival in near-weightless conditions.
Findings offer potential for improving phage therapies on Earth.
The research compared Earth-based and space-based infection dynamics to reveal evolution in action.
The study appears in the journal PLOS Biology and informs space biology.
Researchers see space work as a platform to study microbial adaptation.
The ISS phage research links space exploration to human health applications.

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#2 out of 2

health14h ago

Microgravity altered phage-bacteria infection dynamics, creating mutations not typically seen on Earth.
Space-grown phages and E. coli developed mutations that could boost infection and survival in near-weightless conditions.
Space-driven mutations could improve phage therapy effectiveness against terrestrial pathogens back on Earth.
Researchers used deep mutational scanning to map changes in the phage receptor-binding protein.
Findings were published in the journal PLOS Biology, with space results guiding future Earth-based studies.
Studies indicate microgravity-related patterns may help address antibiotic-resistant infections on Earth.
Study limitations include small sample sizes and space hardware constraints.
Researchers emphasized space as a discovery environment, not a routine testing platform.
The work was partly conducted aboard the International Space Station (ISS).
Expert Raman notes space experiments help reveal patterns useful for terrestrial problems like antimicrobial resistance.

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