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health1d ago
Moleculin Presents ASCO Data Showing No Detectable Cardiotoxicity with Annamycin at High Exposure
- Moleculin reports pooled ASCO data showing no detectable cardiotoxicity from Annamycin at high exposure.
- In 90 patients, LVEF change was not significant (mean diff -0.12%).
- No correlation found between cumulative Annamycin dose and LVEF changes.
- Independent Cleveland Clinic review found no evidence of drug-induced cardiotoxicity.
- Phase 1b/2 AML results show favorable responses reinforcing MIRACLE trial rationale.
- The data come from ASCO presentations and SEC filings about Moleculin Biotech, Inc.
- The summary is AI-generated and should be verified against the source.
- Cumulative dose exposure reached a median of 660 mg/m² in the analysed cohort.
- The ASCO data included 78 patients with paired LVEF measurements.
- The study found no significant LVEF change despite high exposure, supporting safety signals.
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