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First-Of-Its-Kind Organ Transplant Sees Whole Liver And Both Kidneys Successfully Moved From Pig To Human
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health12h ago

First-Of-Its-Kind Organ Transplant Sees Whole Liver And Both Kidneys Successfully Moved From Pig To Human

  • A Chinese team performed the first bilateral liver and kidney transplant using pig organs into a deceased human recipient.
  • The pig organs were gene-edited with six edits to minimize rejection and resemble human organ function.
  • The study followed the patient for five days, reporting initial organ function and early signs of immune activity.
  • Researchers say the results indicate essential hepatic and renal functions depend weakly on the species of the graft, suggesting compatibility between human and pig organs.
  • The study notes this is an initial case with limited follow-up, and broader trials are needed to assess long-term viability.
  • Public interest in xenotransplantation remains high, with a 2024 survey showing broad willingness to accept pig organs among the public.
  • The researchers stressed the need for ongoing follow-up and expansion of cases to determine long-term outcomes.
  • The donation and transplant ecosystem in the US remains a backdrop to these advances, highlighting ongoing organ shortages.
  • The study used organs with six gene edits to reduce rejection and improve compatibility.
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