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A 13-year-old boy has become the first person to be cured of this deadly brain cancer
- Lucas Jemeljanova, a 13-year-old from Belgium, is reported cured of DIPG after the BIOMEDE trial employing everolimus.
- The BIOMEDE trial randomly assigned Lucas to everolimus, a drug that inhibits mTOR to slow cancer growth.
- MRI scans showed the tumor completely disappeared and has not recurred since.
- Experts say the tumor’s disappearance may relate to a rare genetic mutation making cells unusually sensitive to everolimus.
- Seven other children showed long-term responses, with tumors not progressing for more than three years.
- A separate immunotherapy trial also showed tumor shrinkage and functional gains, though results varied by patient.
- Lucas’ doctors in Paris continue monitoring him as the search for replicable results proceeds.
- Lucas and his family previously traveled to France to participate in the BIOMEDE trial.
- The BIOMEDE trial’s success provides renewed hope for DIPG families despite the need for more research.
- The story originally appeared two years ago and has been updated with new details.
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