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A New Study Challenges the Way We Screen for Breast Cancer
- New analysis of the WISDOM study finds personalized, risk-based screening can be as effective as annual mammograms for detecting breast cancer.
- The study enrolled over 28,000 women aged 40 to 74 to test four risk-based screening regimens.
- Women at highest risk receive alternating mammograms and MRIs every six months under the risk-based model.
- The approach uses a risk algorithm incorporating genetic data, breast density, age, and family history.
- Esserman says risk-based screening is a prerequisite to implementation and aims to reduce over-treatment.
- Early results suggest fewer higher-stage cancers (Stage 2B) in the highest-risk group compared with annual screening.
- Experts note that risk-based screening could prevent over-treatment and tailor prevention efforts.
- The research underscores the role of routine genetic testing in identifying high-risk individuals early.
- WISDOM will continue to track treatments and outcomes as it advances risk-based screening.
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