8legs: Jama network open

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Magic mushrooms could be effective treatment for cocaine addiction, study shows

A single psilocybin dose plus therapy increased abstinence from cocaine versus placebo in a randomized trial.
Study published in Jama Network Open compared 19 psilocybin participants to 17 placebo participants.
Researchers and clinicians describe psilocybin as a catalyst within therapy, not a maintenance drug.
The trial included a majority of Black participants, addressing diversity in psychedelic research.
Experts note psilocybin may increase neuroplasticity and psychological flexibility.
There are no FDA-approved medications specifically for cocaine use disorder yet.
The authors caution results may not generalize to people with comorbid depression or anxiety.
Researchers emphasize the need for larger trials to confirm findings across diverse groups.
Both groups in the trial undertook therapy to process experiences during treatment.
Experts suggest psychedelics could help with conditions like depression and anxiety co-occurring with addiction.

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