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Top 2 harvard medical school News Today

#1
Probiotics and Popular Remedies Ineffective for Irritable Bowel Syndrome, Experts Say
#1 out of 2
health12h ago

Probiotics and Popular Remedies Ineffective for Irritable Bowel Syndrome, Experts Say

  • Latest guidance states popular online IBS remedies lack solid scientific backing according to expert voices and review of recent content.
  • Harvard gastroenterologist cautions against relying on unproven remedies like probiotics for IBS treatment.
  • Experts emphasize IBS symptoms can be managed with evidence-based first-line therapies like soluble fiber and hydration.
  • Dietary changes to identify and limit trigger foods can help some IBS patients, the article notes.
  • Peppermint is recommended for mild IBS symptoms by major gastroenterology groups.
  • The report notes that IBS can show normal results on colonoscopy or blood tests despite active gut problems.
  • The article cites a 2024 meta-analysis that found limited benefits from abdominal massage for chronic constipation.
  • Officials discourage at-home gut microbiome tests due to lack of clinical validation.
  • Experts urge consulting a gastroenterologist if first-line treatments fail to relieve IBS symptoms.
  • The Washington Post article by Dr. Trisha Pasricha supports evidence-based IBS treatment and cautions against unverified online claims.
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#2
First-of-its-kind map of the mouse nose reveals surprises about the sense of smell
#2 out of 2
9h ago

First-of-its-kind map of the mouse nose reveals surprises about the sense of smell

  • A comprehensive map of mouse smell receptors shows organized, banded patterns rather than random distribution.
  • Researchers catalog 1,172 odor receptor types across about 1,100 olfactory neurons in mice.
  • Single-cell sequencing and spatial transcriptomics linked nose receptors to brain maps in the olfactory bulb.
  • Retinoic acid may guide neuron placement and receptor expression according to the study.
  • The work aligns nose receptor maps with brain maps in the olfactory bulb, suggesting coordinated organization.
  • The findings elevate our understanding of scent processing and may inform treatments for smell loss.
  • Researchers describe the map as a 'beautiful map' of over 1,100 smell receptors in the nose.
  • The study examined multiple lab mice and found consistent receptor positions across specimens.
  • The research uses advanced methods to explore how genes are active in nose cells and how this relates to smell.
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