8legs: Geneva, switzerland

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#1 out of 4

Scientists reveal the first 3D view of how killer T cells attack cancer inside real tumors.
The study used cryo-expansion microscopy to preserve near-native cell structure during imaging.
Researchers found a dome-like membrane at the T cell contact point linked to adhesion and organization.
The team extended imaging to human tumor tissues to observe T cells infiltrating tumors in situ.
Cytotoxic granules can vary, sometimes containing one or more cores with concentrated active molecules.
The findings may help refine cancer immunotherapies by clarifying immune cell mechanics in tumors.
The study was conducted by UNIGE and CHUV researchers with ISREC TANDEM program support.
The work was published in Cell Reports, detailing molecular architecture of T cells and immune synapses.
The research highlights how the immune synapse coordinates toxic molecule release to target cells.
The findings span from isolated cells to human tumor tissues for clinical relevance.

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#2 out of 4

Watches and Wonders 2026 in Geneva drew nearly 60,000 unique visitors, a record for the show.
Attendance jumped to a record near 60,000 visitors, with 65 brands at Palexpo this year.
Rolex featured the Oyster case anniversary models, including new variants and a Jubilee dial revival.
Parmigiani Fleurier unveiled the Mysterieux chronograph with a hidden-hand mechanism.
TAG Heuer presented the Monaco Evergraph with a new TH80-00 movement and reduced friction.
Grand Seiko showcased the Spring Drive Ushio 300 Diver, offering world-class accuracy in a compact 40.8mm size.
Cartier revived the Roadster model and expanded Santos with new bracelets and finishes.
Patek Philippe marked the Nautilus 50th anniversary with restrained, slim models in precious metals.
Sinn joined Watches and Wonders with the 544, emphasizing value in a robust steel timepiece.
The event underscored a market shift toward value, accessibility, and consumer-focused pricing.

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#3 out of 4

health21h ago

Stern led WHO communications for over six years, steering messaging through the COVID-19 era.
The talk focuses on delivering clear, trusted health messaging during outbreaks and crises.
The interview covers the challenges of communicating during a rapidly changing information environment.
Stern’s experiences highlight leadership in global health messaging and public engagement.
The piece ties messaging to broader issues like funding cuts in global health.

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#4 out of 4

Retailer David Hurley says most Rolex and Patek Philippe releases already drew strong interest before the show.
Rolex enamel-dial Daytona and the new Yacht-Master are the headliners, with other pieces under the radar.
Patek Philippe’s 50th anniversary Nautilus and a World Timer in yellow gold stand out as near-winners.
Tudor’s Monarch and ice-blue Royal are highlighted as strong, wearable releases.
The Cartier Roadster’s return is driven by strong American client demand.
Retailers place most yearly orders before Watches and Wonders based on brand performance.
US market remains the strongest, supporting continued growth in watches as a luxury category.
Retailers observe early, rapid client responses via texts and direct outreach during releases.
Watches and Wonders is described as the major annual moment for many brands and retailers.
The show helps retailers review new brands and see more complicated pieces for future orders.

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