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health22h ago
What will it take to get a vaccine for the Ebola strain driving the current outbreak?
- CEPI and partners sped up Bundibugyo Ebola vaccine development with multi-million dollar funding commitments.
- IAVI, Oxford, and Moderna are advancing vaccine candidates to target Bundibugyo Ebola.
- IAVI's vaccine uses a vesicular stomatitis virus delivery to target Bundibugyo virus.
- Oxford's candidate could be ready within one to two months, pending production.
- Moderna may pursue an mRNA vaccine with up to $50 million in support for Bundibugyo.
- Trials face challenges from the outbreak's spread and ongoing conflict in northeast DRC.
- Community engagement is crucial to enable trial enrollment amid distrust and rumors.
- Researchers stress testing must balance speed with ethical and rigorous standards.
- DRC outbreak remains one of the largest on record, amplifying vaccine urgency.
- WHO and CEPI officials are coordinating trials and community engagement strategies.
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