8legs: Fred hutchinson cancer center

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health17h ago

95% of people carry this virus and scientists may have just found how to stop it

Scientists identified human monoclonal antibodies that block EBV from entering immune cells in a humanized mouse model.
One gp42-targeting antibody fully blocked EBV infection in lab models with human-like immune systems.
The research used a transgenic mouse model to discover protective antibodies against EBV.
Experts see potential for preventive antibody therapy to help transplant patients at high risk of EBV-related complications.
Fred Hutchinson Cancer Center filed intellectual property claims related to the discovered antibodies.
The study, published in Cell Reports Medicine, demonstrates a path toward clinical development of EBV-targeted therapies.
Researchers identified two gp350- and eight gp42-targeting antibodies as key protective agents.
The antibodies block EBV entry by interfering with gp350 and gp42 functions.
The team aims safety testing in healthy adults followed by trials in high-risk patients.
The work contributes to preventing EBV viremia and related diseases in transplant medicine.

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