8legs: Clinical trials on alzheimer’s disease (ctad) conference

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Using Digital Multidomain Lifestyle Interventions for Alzheimer Disease Prevention: Tatsuhiro Hisatsune, PhD | NeurologyLive - Clinical Neurology News and Neurology Expert Insights

A six‑month randomized trial found that personalized wearable‑based notifications improved cognition in older adults compared with usual care.
MoCA scores rose more in the intervention group (change 1.0) than in controls (0.2).
Frailty status improved more with the intervention (−0.3 vs −0.1).
Researchers used wearables and smartphone data to monitor activity and sleep.
Study authors emphasized the burden on caregivers and patients and sought digital solutions to reduce it.
The CTAD 2025 conference provided the backdrop for these findings.
The team discussed preclinical work on anserine as a potential cognitive support.
The findings suggest multidomain interventions could be studied across different populations worldwide.
The study points to wearable-based strategies as a practical approach for monitoring lifestyle factors.
The reference cites a 2025 CTAD abstract and confirms a randomized trial design.

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