8legs: Annals of the american thoracic society

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People taking common sleep drug may not realize they're too impaired to drive, study finds

A small trial found quetiapine reduced sleep apnea events and increased total sleep time in adults with OSA.
Despite sleep improvements, driving and attention deteriorated after waking, with more than triple attention lapses in the driving test.
Researchers warn next-day impairment after quetiapine may affect safety-critical tasks for up to about 9.5 hours.
The study included 15 adults with sleep apnea who underwent two overnight sleep studies about a week apart.
Women may metabolize these drugs more slowly, potentially influencing efficacy and next‑day side effects.
Experts say behavioral therapies remain important for long-term insomnia management despite short-term drug benefits.
The study team calls for larger, longer-term research before prescribing changes for sleep apnea.
Participants reported feeling sleepier the morning after taking quetiapine.
The study used a driving simulator to assess next-day driving performance.

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