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health3h ago
Researchers discover potential breakthrough treatment for rare condition Céline Dion lives with
- New SPS therapy using CAR T-cells shows potential to treat rare stiff-person syndrome, a breakthrough discussed at a neurology conference.
- Researchers say the therapy resets the immune system by depleting misbehaving B-cells and rebuilding healthy ones.
- Céline Dion's 2022 SPS diagnosis links to funding that supported the new potential therapy.
- Early trial results showed improved mobility four months after treatment in SPS patients.
- The researchers caution that long-term durability of the therapy remains to be studied.
- The SPS trial involved 26 adults and was presented at a major neurology meeting in 2026.
- SPS can cause progressive muscle stiffness and difficulties with breathing, swallowing, and speaking.
- CAR T-cell therapy is commonly used in cancer but is being explored for SPS in this research.
- The research highlights the potential of SPS treatment to reduce dependence on walking aids.
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