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Women with osteoporosis 'more likely to carry Alzheimer's risk gene'
- A study finds osteoporosis in women may be linked to carrying the APOE4 Alzheimer's risk gene.
- Researchers observed APOE4 elevated in bone cells (osteocytes) of older female mice.
- The study links bone molecular changes to brain disease risk, even when scans look normal.
- Findings may enable earlier detection of both osteoporosis and Alzheimer's in women.
- The research team emphasizes a sex-specific impact on bone and brain tissue.
- Experts see the body as an interconnected system, not treating diseases in isolation.
- The study appears in Advanced Science, with researchers from Buck Institute and UC San Francisco.
- Bone cells may serve as early indicators of cognitive decline in APOE4 carriers.
- The research notes higher Alzheimer's risk is linked with skeletal health in women.
- The article discusses potential targets for preserving bone quality in APOE4 carriers.
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