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https://www.theguardian.com/science/2025/aug/25/surgeons-transplant-pig-lung-into-brain-dead-human-recipient-for-first-timehttps://www.cnn.com/2025/08/25/health/first-pig-to-human-lung-transplanthttps://www.statnews.com/2025/08/25/first-lung-xenotransplant-gene-edited-pig/
Theguardian.com and 7 more
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Highlights
  • The pig lung xenograft remained viable and functional over 216 hours, with no hyperacute rejection or infection during the 9-day monitoring window.
  • Antibody-mediated rejection contributed to xenograft damage on postoperative days 3 and 6, with partial recovery by day 9, underscoring immune-driven injury as a core barrier.
  • Researchers used CRISPR-edited pigs, disabling three pig genes and adding three human genes to improve tolerance to the human body.

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References

Surgeons transplant pig lung into brain dead human recipient for first time

https://www.theguardian.com/science/2025/aug/25/surgeons-transplant-pig-lung-into-brain-dead-human-recipient-for-first-timeTheguardian.com
Surgeons transplant pig lung into brain dead human recipient for first time

For the first time, a genetically modified pig lung was transplanted into a brain-dead man | CNN

https://www.cnn.com/2025/08/25/health/first-pig-to-human-lung-transplantCnn.com
For the first time, a genetically modified pig lung was transplanted into a brain-dead man | CNN

Gene-edited pig lung transplanted into a brain-dead patient for first time

https://www.statnews.com/2025/08/25/first-lung-xenotransplant-gene-edited-pig/Statnews.com
Gene-edited pig lung transplanted into a brain-dead patient for first time

Scientists perform the first pig-to-human lung transplant

https://www.sciencenews.org/article/first-pig-to-human-lung-transplantSciencenews.org
Scientists perform the first pig-to-human lung transplant

Pig-to-human lung xenotransplantation into a brain-dead recipient - Nature Medicine

https://www.nature.com/articles/s41591-025-03861-xNature.com
Pig-to-human lung xenotransplantation into a brain-dead recipient - Nature Medicine

First-ever pig-to-human lung transplant attempted in brain-dead person in China

https://www.livescience.com/health/surgery/first-ever-pig-to-human-lung-transplant-attempted-in-brain-dead-person-in-chinaLivescience.com
First-ever pig-to-human lung transplant attempted in brain-dead person in China

Scientists transplant a PIG lung into a human in world-first operation

https://www.dailymail.co.uk/sciencetech/article-15031099/Scientists-transplant-PIG-lung-human-op.htmlDailymail.co.uk
Scientists transplant a PIG lung into a human in world-first operation

Related Topics

healthscienceguangzhou, china

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