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health3h ago
Scientists discover hidden driver of aging — Simple supplement reversed brain decline
- Researchers found aging signs in mice linked to a decline of Menin in the hypothalamus, triggering inflammation and memory loss.
- Restoring Menin in elderly mice reversed several aging symptoms within 30 days, including learning and balance.
- D-serine supplementation boosted cognition in aged mice, linking another path to cognitive improvement.
- The hypothalamus may act as a central command center for aging, coordinating inflammation, metabolism, and hormones.
- The study was conducted in mice, and it remains unknown whether Menin or D-serine will help humans.
- Menin loss specifically affected ventromedial hypothalamic neurons, not nearby astrocytes or microglia.
- D-serine connects Menin to cognitive processes by supporting serine synthesis linked to memory.
- The research team delivered the Menin gene directly into the hypothalamus of aged mice to test reversal effects.
- Experts urge caution, noting the findings are early and not yet applicable to human aging.
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